Nanotechnology-Based Cisplatin Intracellular Delivery to Enhance Chemo-Sensitivity of Ovarian Cancer.
Barbara BortotMaurizio MongiatErica ValencicSimeone Dal MonegoDanilo LicastroMatteo CroseraGianpiero AdamiEnrico RampazzoGiuseppe RicciFederico RomanoGiovanni Maria SeveriniStefania BiffiPublished in: International journal of nanomedicine (2020)
Nanoparticle-mediated cisplatin delivery may serve as an intracellular depot impacting the cisplatin pharmacodynamic performance at cellular levels. These features may contribute to improving the drawbacks of conventional intraperitoneal therapy, and therefore will require further investigations in vivo.