Midkine promotes glioblastoma progression via PI3K-Akt signaling.

Beiquan HuChao QinLi LiLei WeiXianlun MoHuasheng FanYuanhua LeiFeng WeiDong-Hua Zou

Published in: Cancer cell international (2021)

Our present study proposes that MDK promotes GBM by activating the PI3K-Akt signaling pathway, and it describes a potential regulatory network involved.

Keyphrases

signaling pathway
pi k akt
cell cycle arrest
induced apoptosis
epithelial mesenchymal transition
cell proliferation
transcription factor
oxidative stress