Asymmetric Total Synthesis of Fawcettimine-Type Lycopodium Alkaloid, Lycopoclavamine-A.
Hiroki KanekoShunsuke TakahashiNoriyuki KogureMariko KitajimaHiromitsu TakayamaPublished in: The Journal of organic chemistry (2019)
An asymmetric total synthesis of lycopoclavamine-A (1), a structurally unique fawcettimine-type Lycopodium alkaloid, was achieved via a stereoselective Pauson-Khand reaction and a stereoselective conjugate addition to construct a quaternary carbon center at C-12.
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