Delayed Kinetics of IgG, but Not IgA, Antispike Antibodies in Transplant Recipients following SARS-CoV-2 Infection.
Paolo CravediPatrick AhearnLin WangTanuja YalamartiSusan HartzellYorg AzziMadhav C MenonAditya JainMarzuq BillahMarcelo Fernandez-VinaHoward M GebelE Steve WoodleNatalie S HaddadAndrea Morrison-PorterF Eun-Hyung LeeIgnacio SanzEnver AkalinAlin GirnitaJonathan S MaltzmanPublished in: Journal of the American Society of Nephrology : JASN (2021)
Kidney transplant recipients mount early anti-SARS-CoV-2 IgA and IgM responses, whereas IgG responses are delayed compared with immunocompetent individuals. These findings might explain the poor outcomes in transplant recipients with COVID-19.