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Exploring resting state connectivity in patients with psychotic depression.

Mardien L OudegaYsbrand D van der WerfAnnemieke DolsMike P WattjesFrederik BarkhofFilip BouckaertMathieu VandenbulckeFrançois-Laurent De WinterPascal SienaertPiet EikelenboomMax L StekOdile A van den HeuvelLouise EmsellDidi RhebergenEric van Exel
Published in: PloS one (2019)
Psychotic depression may be associated with decreased FC of the frontoparietal network, which is involved in cognitive control processes, such as attention and emotion regulation. These findings suggest that FC in the frontoparietal network may be related to the subtype of depression, i.e. presence of psychotic symptoms, rather than severity of depression. Since the findings could not be replicated in the 2nd sample, replication is needed before drawing definite conclusions.
Keyphrases
  • resting state
  • functional connectivity
  • depressive symptoms
  • sleep quality
  • bipolar disorder
  • white matter