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Disentangling discordant vitamin D associations with prostate cancer incidence and fatality in a large, nested case-control study.

Lola EtiévantMitchell H GailDemetrius Albanes
Published in: International journal of epidemiology (2024)
We found evidence of neither artefacts in the nested prostate cancer case-control data set nor detection or collider biases in the fatality analyses. The present findings therefore support a valid inverse (i.e. beneficial) association between vitamin D and prostate cancer-specific survival that warrants further evaluation, including possibly in controlled trials.
Keyphrases
  • prostate cancer
  • case control
  • radical prostatectomy
  • risk factors
  • electronic health record
  • big data
  • artificial intelligence
  • label free
  • loop mediated isothermal amplification
  • quantum dots
  • clinical evaluation