Low Shear Stress at Baseline Predicts Expansion and Aneurysm-Related Events in Patients With Abdominal Aortic Aneurysm.
Nikhilesh BappooMaaz B J SyedGeorgia KhinsoeLachlan J KelseyRachael O ForsytheJanet T PowellPeter R HoskinsOlivia M B McBridePaul E NormanShirley JansenDavid E NewbyBarry J DoylePublished in: Circulation. Cardiovascular imaging (2021)
We show for the first time that low shear stress (<0.4 Pa) at baseline is associated with both AAA expansion and future aneurysm-related events. Aneurysms within the lowest tertile of shear stress, versus those with higher shear stress, were more likely to rupture or reach thresholds for elective repair. Larger prospective validation trials are needed to confirm these findings and translate them into clinical management.