Survival associated with the use of sentinel lymph node in addition to lymphadenectomy in early-stage cervical cancer treated with surgery alone: A sub-analysis of the Surveillance in Cervical CANcer (SCCAN) collaborative study.
Nicolò BizzarriDenis QuerleuPedro T RamirezLukáš DostálekLuc Rc W van LonkhuijzenDiana GiannarelliAldo LopezSahar SalehiAli AyhanSarah H KimDavid Isla OrtizJaroslav KlatFabio LandoniRene ParejaRanjit ManchandaJan KosťunMehmet M MeydanliDiego OdettoRene LakyIgnacio ZapardielVit WeinbergerRicardo Dos ReisLuigi Pedone AnchoraKarina AmaroHuseyin AkilliNadeem R Abu-RustumRosa A Salcedo-HernándezVeronika JavůrkováConstantijne H MomHenrik FalconerGiovanni ScambiaDavid CibulaPublished in: European journal of cancer (Oxford, England : 1990) (2024)
Adding SLN biopsy to pelvic lymphadenectomy was associated with lower recurrence and death rate and improved 5-year DFS. This might be explained by the lower rate of missed nodal metastasis thanks to the use of SLN ultrastaging. SLN biopsy should be recommended in patients with early-stage cervical cancer.