Predictive biomarkers of ossification progression and bone metabolism dynamics in patients with cervical ossification of the posterior longitudinal ligament.
Keiichi KatsumiKei WatanabeAkiyoshi YamazakiToru HiranoMasayuki OhashiTatsuki MizouchiMasayuki SatoHiroyuki SekimotoTomohiro IzumiYohei ShibuyaHiroyuki KawashimaPublished in: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society (2023)
Younger age, hypophosphatemia, and high serum sclerostin are risk factors for OPLL progression. Serum phosphorus and sclerostin could serve as important biomarkers for predicting ossification progression.
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