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Quality control and stability of ketamine, remifentanil, and sufentanil syringes in a pediatric operating theater.

Florence BourdonNicolas SimonDamien LannoyChristophe BerneronBertrand DécaudinLaurence ReumauxAlain DuhamelPierre RichartPascal Odou
Published in: Paediatric anaesthesia (2019)
The study shows that stock solution syringes prepared in advance are chemically stable throughout the day, unlike certain serial dilution syringes, indicating that the latter should be prepared just before administration to ensure chemical stability. Our results show that the error rate for serial dilution syringes is twice that of stock solution. Different safety measures are under discussion and have to be further studied.
Keyphrases
  • quality control
  • liquid chromatography tandem mass spectrometry
  • liquid chromatography
  • gas chromatography
  • pain management
  • ms ms
  • simultaneous determination