Low dose radiotherapy is associated with local complications but not disease control in sacral chordoma.

Matthew T HoudekPeter S RoseMario HevesiJoseph H SchwabAnthony M GriffinJohn H HealeyIvy A PetersenThomas F DeLaneyPeter W ChungMichael J YaszemskiJay S WunderFrancis J HornicekPatrick J BolandFranklin H SimPeter C Fergusonnull null

Published in: Journal of surgical oncology (2019)

In this multicenter review, radiotherapy was not associated with tumor outcome but associated with complications. The routine use of radiotherapy with en-bloc resection of sacrococcygeal chordomas should be reconsidered in favor of a selective, individualized approach with a radiation dose of ≥70 Gy.

Keyphrases

early stage
low dose
locally advanced
radiation induced
radiation therapy
risk factors
rectal cancer
high dose
clinical trial