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Sodium Valproate Induced Alopecia: A Case Series.

Sereen Rose ThomsonVinay MamulpetShalini Adiga
Published in: Journal of clinical and diagnostic research : JCDR (2017)
Drug induced alopecia may range from a barely detectable shedding to an irreversible baldness. Alopecia associated with valproate is a dose-dependent and reversible side effect. We hereby report, three cases of alopecia that occurred in patients who received sodium valproate for various neurological conditions. In all three cases, long term exposure of valproate therapy led to the development of alopecia which eventually resolved after dose reduction or discontinuation. The Naranjo's causality assessment scale indicated valproate as the probable cause of the alopecia in all our patients.
Keyphrases
  • drug induced
  • liver injury
  • end stage renal disease
  • chronic kidney disease
  • newly diagnosed
  • emergency department
  • diabetic rats
  • mesenchymal stem cells