Effect of thymoquinone on sepsis-induced cardiac damage via anti-inflammatory and anti-apoptotic mechanisms.
Wenyan GuoXiaofeng LongMingyi LvShuling DengDuping LiuQin YangPublished in: The Journal of international medical research (2022)
These results suggest that TQ effectively modulates pro-inflammatory, apoptotic, oxidative stress, and PI3K/AKT pathways, making it indispensable in the treatment of sepsis-induced cardiac damage.
Keyphrases
- oxidative stress
- diabetic rats
- pi k akt
- anti inflammatory
- cell death
- signaling pathway
- high glucose
- acute kidney injury
- intensive care unit
- cell cycle arrest
- left ventricular
- septic shock
- cell proliferation
- drug induced
- dna damage
- heart failure
- ischemia reperfusion injury
- endothelial cells
- induced apoptosis
- heat shock
- replacement therapy
- heat stress