The complete mitochondrial genome of Talpa aquitania (Talpidae; Insectivora), a mole species endemic to northern Spain and southern France.
Gaël Aleix-MataJuana GutiérrezFrancisco J Ruiz-RuanoPedro LoriteJuan A MarchalAntonio Sánchez BacaPublished in: Molecular biology reports (2020)
The complete mitogenome sequence of Talpa aquitania, a recently described Talpa species, was assembled using whole-genome sequencing data. It varies in length from 16,776 to 16,846 bp, contains 13 protein-coding genes, two ribosomal RNA genes, 22 transfer RNA genes, one origin of L-strand replication, and a control region. In the control region, which varied from 1320 to 1390 bp, we identified the extended termination-associated sequence (ETAS-1 and ETAS-2) and the conserved sequence blocks (CSB-1, 2, 3, B, C, D, E, F). In addition, this region includes a 10 bp tandem repeat DNA sequence, with a variable number of repeats that suggest the existence of heteroplasmy. Phylogeny reconstructions based on Maximum Likelihood, Neighbor-joining and Bayesian inference analyses yielded phylogenies with similar topologies demonstrating that T. aquitania and T. occidentalis are sister species.
Keyphrases
- genome wide
- amino acid
- genome wide identification
- bioinformatics analysis
- oxidative stress
- mitochondrial dna
- dna methylation
- nucleic acid
- gene expression
- genome wide analysis
- dna repair
- magnetic resonance imaging
- circulating tumor
- small molecule
- cell free
- dna damage
- deep learning
- artificial intelligence
- circulating tumor cells