Oxidative Stress and Endoplasmic Reticulum Stress in Rare Respiratory Diseases.
María MagallónAna Esther CarriónLucía BañulsDaniel PellicerSilvia Castillo-CorullonSergio BondíaMaría Mercedes Navarro-GarcíaCruz GonzálezFrancisco DasíPublished in: Journal of clinical medicine (2021)
Several studies have shown that some rare respiratory diseases, such as alpha-1 antitrypsin deficiency (AATD), idiopathic pulmonary fibrosis (IPF), cystic fibrosis (CF), and primary ciliary dyskinesia (PCD) present oxidative stress (OS) and endoplasmic reticulum (ER) stress. Their involvement in these pathologies and the use of antioxidants as therapeutic agents to minimize the effects of OS are discussed in this review.
Keyphrases
- idiopathic pulmonary fibrosis
- endoplasmic reticulum stress
- induced apoptosis
- cystic fibrosis
- oxidative stress
- endoplasmic reticulum
- interstitial lung disease
- pseudomonas aeruginosa
- dna damage
- ischemia reperfusion injury
- diabetic rats
- lung function
- signaling pathway
- respiratory tract
- replacement therapy
- systemic sclerosis
- case control
- chronic obstructive pulmonary disease
- air pollution
- rheumatoid arthritis