Practitioner Review: Pharmacological treatment of attention-deficit/hyperactivity disorder symptoms in children and youth with autism spectrum disorder: a systematic review and meta-analysis.

Rebecca RodriguesMeng-Chuan LaiAdam BeswickDaniel A GormanEvdokia AnagnostouPeter SzatmariKelly K AndersonStephanie H Ameis

Published in: Journal of child psychology and psychiatry, and allied disciplines (2020)

Direct pooled evidence supports the efficacy and tolerability of methylphenidate or atomoxetine for treatment of ADHD symptoms in children and youth with ASD. The current review highlights the efficacy of standard ADHD pharmacotherapy for treatment of ADHD symptoms in children and youth with ASD. Consideration of the benefits weighed against the limitations of safety/efficacy data and lack of data evaluating long-term continuation is undertaken to help guide clinical decision-making regarding treatment of co-occurring ADHD symptoms in children and youth with ASD.

Keyphrases

attention deficit hyperactivity disorder
autism spectrum disorder
young adults
working memory
mental health
decision making
combination therapy
machine learning
depressive symptoms
big data
clinical trial
sleep quality
study protocol
replacement therapy
double blind