EGFR Targeted Cetuximab-Valine-Citrulline (vc)-Doxorubicin Immunoconjugates- Loaded Bovine Serum Albumin (BSA) Nanoparticles for Colorectal Tumor Therapy.

Zixuan YeYue ZhangYuanfen LiuYanyan LiuJiasheng TuYan Shen

Published in: International journal of nanomedicine (2021)

The obtained results emphasize that cetuximab-vc-DOX-NPs, with good tumor-targeting ability and low systemic toxicity, are a promising targeting system for drug delivery.

Keyphrases

cancer therapy
drug delivery
small cell lung cancer
metastatic colorectal cancer
drug release
oxidative stress
epidermal growth factor receptor
locally advanced
tyrosine kinase
wild type
squamous cell carcinoma
mesenchymal stem cells
oxide nanoparticles