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Effect of sustained measurable residue disease negativity and post-remission treatment selection on the prognosis of acute lymphoblastic leukemia in adults.

Jiechen YuYanrong LuoLibing WangTao WangMingyu YeJie ChenXiong NiLi ChenLei GaoJian-Min Yang
Published in: Cancer medicine (2024)
B-ALL patients who achieve sustained MRD negativity during consolidation therapy have excellent long-term outcomes even without allo-HSCT. Allo-HSCT is associated with a significant benefit in terms of OS and DFS for patients who were with positive MRD during consolidation therapy.
Keyphrases
  • acute lymphoblastic leukemia
  • hematopoietic stem cell
  • systemic lupus erythematosus
  • replacement therapy
  • combination therapy