Concurrent immunotherapy and re-irradiation utilizing stereotactic body radiotherapy for recurrent high-grade gliomas.

Sean S MahaseMichelle RoytmanDiana Roth O'BrienJana IvanidzeTheodore H SchwartzSusan C PannulloRohan RamakrishnaRajiv S MaggeNicholas WilliamsHoward A FineGloria Chia-Yi ChiangJonathan P S Knisely

Published in: Cancer reports (Hoboken, N.J.) (2023)

In this heavily pretreated cohort, ICI with re-irradiation utilizing SBRT was well tolerated. Prospective studies are warranted to evaluate potential therapeutic benefits to re-irradiation with ICI + SBRT in rHGG.

Keyphrases

high grade
radiation therapy
radiation induced
low grade
locally advanced
early stage
squamous cell carcinoma
case control