Inhibition of viral and bacterial trigger-stimulated prostaglandin E2 by a throat lozenge containing flurbiprofen: An in vitro study using a human respiratory epithelial cell line.

Robert Lambkin-Williams Alexander MannAdrian Shephard

Published in: SAGE open medicine (2020)

A549 cells provide a suitable model for assessment of prostaglandin E2 stimulation by viral and bacterial triggers. Diluted flurbiprofen-containing lozenges demonstrated rapid anti-inflammatory activity in viral- and lipopolysaccharide/peptidoglycan-stimulated A549 cells.

Keyphrases

induced apoptosis
sars cov
cell cycle arrest
endothelial cells
endoplasmic reticulum stress
immune response
cell proliferation
induced pluripotent stem cells
sensitive detection
respiratory tract