Heparin-binding protein levels correlate with aggravation and multiorgan damage in severe COVID-19.

Mingshan XueYifeng ZengHui-Qi QuTeng ZhangNing LiHuimin HuangPeiyan ZhengHaisheng HuLuqian ZhouZhifeng DuanYong ZhangWei BaoLi-Feng TianHakon HakonarsonNanshan ZhongXiaohua Douglas ZhangBaoqing Sun

Published in: ERJ open research (2021)

HBP levels are associated with COVID-19 disease progression in critically ill patients. As a potential mediator of disease aggravation and multiple organ injuries that are triggered by continuing inflammation and oxygen deficits, HBP warrants further study as a disease biomarker and potential therapeutic target.

Keyphrases

coronavirus disease
sars cov
binding protein
oxidative stress
traumatic brain injury
human health
venous thromboembolism
early onset
risk assessment
respiratory syndrome coronavirus
climate change
drug induced
medical education