Glutathione S transferase T1 gene polymorphism and its promoter methylation are associated with breast cancer susceptibility in Egyptian women.

Nermin RaafatKhadiga IsmailNahed M HawsawiTaisir SaberWael H ElsawyTariq AbdulmutalebAhmed RaafatAmal F Gharib

Published in: Biotechnology and applied biochemistry (2021)

GSTT1 null genetic variant and promoter hypermethylation in the GSTT region of the gene may be considered as critical risk factors for BC in Egyptian women.

Keyphrases

dna methylation
genome wide
polycystic ovary syndrome
breast cancer risk
gene expression
transcription factor
pregnancy outcomes
copy number
cervical cancer screening
insulin resistance
pregnant women
metabolic syndrome
adipose tissue
young adults