Hydrophilic biomaterial intravenous hydrogel catheter for complication reduction in PICC and midline catheters.
Nancy L MoureauPublished in: Expert review of medical devices (2024)
Patients commonly require PICC or midline catheters for treatment to establish a reliable form of intravenous access. Catheters, while reliable in most cases, are not without complications, including occlusion, thrombosis and infection, each related to cellular adherence to the catheter material. Hydrophilic catheter coatings and composites have been developed to mitigate these thrombotic complications, reduce adherence of blood and bacterial cells to catheters and provide greater patient safety with these devices. Hydrogel materials are highly biocompatible and have been effective in reducing cellular adherence and the formation of biofilms on surfaces. Smooth hydrophilic catheter surfaces are potentially more comfortable for the patient, with reduced friction during insertion and removal. A catheter constructed of hydrophilic biomaterial, a hydrogel composite material, may minimize thrombotic complications in PICC and midline catheters, improving catheter performance and outcomes for patients.
Keyphrases
- patient safety
- end stage renal disease
- ejection fraction
- liquid chromatography
- ultrasound guided
- drug delivery
- newly diagnosed
- prognostic factors
- risk factors
- type diabetes
- high dose
- pulmonary embolism
- wastewater treatment
- metabolic syndrome
- patient reported outcomes
- quality improvement
- escherichia coli
- oxidative stress
- glycemic control
- cell proliferation
- ionic liquid
- signaling pathway
- combination therapy