Impaired coronary microcirculation is associated with left ventricular diastolic dysfunction in end-stage chronic kidney disease patients.
Nikos PapamichailAris BechlioulisLampros LakkasMara BougiakliSophia GiannitsiChariklia GouvaKostas KatopodisLampros K MichalisKaterina K NakaPublished in: Echocardiography (Mount Kisco, N.Y.) (2020)
In end-stage CKD patients on hemodialysis without known cardiovascular disease, impaired coronary vascular function was prevalent and related to increased left ventricular wall thickness, increased filling pressures, and dipyridamole-induced deteriorated myocardial function independently of the presence of wall-motion abnormalities. Further studies are required to clarify the prognostic role of dipyridamole-induced cardiac changes in hemodialysis patients.
Keyphrases
- end stage renal disease
- chronic kidney disease
- left ventricular
- ejection fraction
- peritoneal dialysis
- cardiovascular disease
- aortic stenosis
- newly diagnosed
- heart failure
- coronary artery disease
- coronary artery
- acute myocardial infarction
- hypertrophic cardiomyopathy
- oxidative stress
- diabetic rats
- high glucose
- prognostic factors
- drug induced
- mass spectrometry
- mitral valve
- patient reported outcomes
- cardiovascular risk factors
- high speed