Characterization of tumor-derived mesenchymal stem cells potentially differentiating into cancer-associated fibroblasts in lung cancer.

Sabrina Arena M Salati G Sorgentoni F Barbisan Monia Orciani

Published in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (2018)

MSCs isolated from tumor tissue displayed distinct properties compared to MSCs isolated from healthy tissue, suggesting T-MSCs differentiation towards a CAF-related phenotype under the influence of the tumoral microenvironment.

Keyphrases

mesenchymal stem cells
umbilical cord
stem cells
magnetic resonance imaging
computed tomography
contrast enhanced
magnetic resonance