Kinetics of immune responses to the AZD1222/Covishield vaccine with varying dose intervals in Sri Lankan individuals.
Chandima JeewandaraInoka Sepali AberathnaLaksiri GomesPradeep Darshana PushpakumaraSaubhagya DanasekaraDinuka GurugeThushali RanasingheBanuri GunasekeraAchala KamaladasaHeshan KuruppuGayasha SomathilakeOsanda DissanayakeNayanathara GamalathDinithi EkanayakeJeewantha JayamaliDeshni JayathilakaAnushika MudunkotuwaMichael HarvieThashmi NimashaRuwan WijayamuniLisa SchimanskiPramila RijalTiong K TanTao DongAlain TownsendGraham S OggGathsaurie Neelika MalavigePublished in: Immunity, inflammation and disease (2022)
Both dosing schedules resulted in high antibody and T cell responses post vaccination, although those with a longer dosing gap had a higher magnitude of responses, possibly as immune responses were measured 6 weeks post second dose compared to 12 weeks post second dose.
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