Impact on childhood mortality of interventions to improve drinking water, sanitation, and hygiene (WASH) to households: Systematic review and meta-analysis.
Hugh Sharma WaddingtonEdoardo MassetSarah BickSandy CairncrossPublished in: PLoS medicine (2023)
The findings are congruent with theories of infectious disease transmission. Washing with water presents a barrier to respiratory illness and diarrhoea, which are the two biggest contributors to all-cause mortality in childhood in L&MICs. Community-wide sanitation halts the spread of diarrhoea. We observed that evidence synthesis can provide new findings, going beyond the underlying data from trials to generate crucial insights for policy. Transparent reporting in trials creates opportunities for research synthesis to answer questions about mortality, which individual studies of interventions cannot be reliably designed to address.
Keyphrases
- drinking water
- infectious diseases
- health risk
- health risk assessment
- cardiovascular events
- healthcare
- physical activity
- mental health
- irritable bowel syndrome
- early life
- risk factors
- public health
- electronic health record
- childhood cancer
- adverse drug
- emergency department
- machine learning
- type diabetes
- coronary artery disease
- data analysis
- risk assessment
- case control
- oral health