The nanoscale organization of reticulon 4 shapes local endoplasmic reticulum structure in situ .

Lukas A Fuentes Zach MarinJonathan TysonDavid Baddeley Joerg Bewersdorf

Published in: bioRxiv : the preprint server for biology (2023)

Rtn4 forms linear-shaped oligomers that contain an average of five Rtn4 proteins, localize to the sides of elliptical tubules, prefer orientations near parallel to the tubule axis, and increase local curvature of the ER membrane by increasing local Rtn4 density.

Keyphrases

endoplasmic reticulum
atomic force microscopy
high resolution
estrogen receptor
high speed
single molecule