A First Case of Acute Cerebellitis Associated with Coronavirus Disease (COVID-19): a Case Report and Literature Review.
Nima FadakarSara GhaemmaghamiSeyed Masoom MasoompourBabak Shirazi YeganehAli AkbariSedighe HooshmandiVahid Reza OstovanPublished in: Cerebellum (London, England) (2020)
Novel coronavirus (severe acute respiratory syndrome-coronavirus-2: SARS-CoV-2), which originated from Wuhan, China, has spread to the other countries in a short period of time. We report a 47-year-old male who was admitted to our hospital due to suffering from progressive vertigo and ataxia for 7 days prior to the admission. Neurological examination revealed cerebellar dysfunction, and brain magnetic resonance imaging (MRI) depicted edema of the cerebellar hemisphere associated with leptomeningeal enhancement. Cerebrospinal fluid (CSF) analysis showed mild lymphocytic pleocytosis, elevated protein, and lactate dehydrogenase. SARS-CoV-2 RNA was detected in the oropharyngeal/nasopharyngeal and CSF specimens. As a result, treatment with lopinavir/ritonavir was initiated, and patient symptoms and signs improved significantly during the course of hospitalization. To the best of our knowledge, this is the first case of acute cerebellitis associated with COVID-19 disease which is reported in the literature so far.
Keyphrases
- respiratory syndrome coronavirus
- coronavirus disease
- sars cov
- cerebrospinal fluid
- magnetic resonance imaging
- liver failure
- respiratory failure
- healthcare
- contrast enhanced
- emergency department
- aortic dissection
- systematic review
- drug induced
- multiple sclerosis
- computed tomography
- oxidative stress
- cerebral ischemia
- early onset
- physical activity
- small cell lung cancer
- resting state
- binding protein
- acute respiratory distress syndrome
- extracorporeal membrane oxygenation
- intensive care unit
- blood brain barrier