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Chronic myeloid leukemia with complex karyotypes: Prognosis and therapeutic approaches.

Ali Amin AsnafiZeinab Deris ZayeriSaeid ShahrabiKazem ZibaraTina Vosughi
Published in: Journal of cellular physiology (2018)
CML classification using different features such as Ph and ACAs can play a decisive role in the evaluation of treatment responses in patients, for example, CML patients with Ph negative and monosomy 7 develop MDS or CML patient -Y and extra copy of Ph have a good response to tyrosine kinase inhibitors, therefore, classifications according to Ph and ACAs play an important role in choosing better treatment protocols and therapeutic strategies. Karyotype analysis in CML patients with complex karyotype shows unrandom pattern so ACAs can be great clue in medical guidelines.
Keyphrases
  • chronic myeloid leukemia
  • ejection fraction
  • machine learning
  • healthcare
  • newly diagnosed
  • deep learning
  • chronic kidney disease
  • combination therapy