Combining SARS-CoV-2 interferon-gamma release assay with humoral response assessment to define immune memory profiles.

William MoutonGuy OriolChristelle CompagnonCarla Saade Kahina SakerPriscille FrancBouchra MokdadAurore FleurieXavier LacouxSoizic DanielFranck BerthierCécile BarnelBruno Pozzetto Jean-Baptiste Fassier Valérie Dubois Sophia Djebali Maxence Dubois Thierry Walzer Jacqueline Marvel Karen Brengel-Pesce Sophie Touillet-Assantnull null

Published in: European journal of immunology (2024)

The discrepancy between humoral and cellular responses highlights the significance of assessing the overall adaptive immune response. This integrated approach allows the identification of vulnerable subjects and can be of interest to guide antiviral prophylaxis at an individual level.

Keyphrases

immune response
sars cov
dendritic cells
toll like receptor
respiratory syndrome coronavirus
high throughput
working memory
bioinformatics analysis
coronavirus disease
clinical evaluation