Login / Signup

The impact of EGFR-TKI use on clinical outcomes of lung adenocarcinoma patients with brain metastases after Gamma Knife radiosurgery: a propensity score-matched analysis based on extended JLGK0901 dataset (JLGK0901-EGFR-TKI).

Shoji YomoToru SerizawaMasaaki YamamotoYoshinori HiguchiYasunori SatoTakashi ShutoAtsuya AkabaneHidefumi JokuraJun KawagishiHidefumi Aoyama
Published in: Journal of neuro-oncology (2019)
Although patients receiving EGFR-TKI concurrently or after SRS had significantly longer OS, the local treatment efficacy and toxicity of SRS did not differ between patients with/without EGFR-TKI use.
Keyphrases
  • tyrosine kinase
  • small cell lung cancer
  • brain metastases
  • epidermal growth factor receptor
  • advanced non small cell lung cancer
  • oxidative stress