Deletion at 2q14.3 is associated with worse response to TNF-α blockers in patients with rheumatoid arthritis.

Ki-Nam GuSo-Young BangHye-Soon LeeYoungho ParkJu-Yeon KangJi-Soong KimBora NamHyun-Seung YooJung-Min ShinYeon-Kyung LeeTae-Han LeeSehwan ChunSoo-Kyung ChoChan-Bum ChoiYoon-Kyoung SungTae-Hwan KimJae-Bum JunDae Hyun YooKwangwoo KimSang-Cheol Bae

Published in: Arthritis research & therapy (2019)

This study obtained the CNV landscape of Korean patients with RA and identified the common regional deletion associated with poor response to treatment with TNF-α blockers.

Keyphrases

rheumatoid arthritis
angiotensin converting enzyme
disease activity
single cell
systemic lupus erythematosus