Sex-specific transcriptome differences in a middle-aged frailty cohort.

Natasha L PachecoNicole Noren HootenYongqing ZhangCalais S PrinceNicolle A ModeNgozi EzikeKevin G BeckerAlan B ZondermanMichele Kim Evans

Published in: BMC geriatrics (2022)

Our results indicate sex-specific transcriptional changes occur in middle-aged frailty, enhancing knowledge on frailty progression and potential therapeutic targets to prevent frailty.

Keyphrases

middle aged
community dwelling
gene expression
healthcare
rna seq
single cell
transcription factor
genome wide
oxidative stress
risk assessment
heat shock
human health