Whole brain radiotherapy combined with intrathecal liposomal cytarabine for leptomeningeal metastasis-a safety analysis and validation of the EANO-ESMO classification.

Sarah IglsederMartha NowosielskiGabriel BstehArmin MuiggJohanna HeugenhauserElke MayerAstrid GramsGünther StockhammerMeinhard Nevinny-Stickel

Published in: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] (2022)

In this retrospective analysis, combined treatment of WBRT and intrathecal liposomal cytarabine shows an acceptable safety profile and may indicate a trend towards improved efficacy. The EANO-ESMO classification for diagnosis and treatment response predicts survival.

Keyphrases

acute myeloid leukemia
deep learning
machine learning
high dose
early stage
brain metastases
radiation therapy
white matter
locally advanced
small cell lung cancer
resting state
cerebrospinal fluid
free survival
rectal cancer