The Hypertension Related Gene G-Protein Coupled Receptor Kinase 4 Contributes to Breast Cancer Proliferation.

Wei YueHanh T TranJi-Ping WangKatherine SchiermeyerJohn J GildeaPeng XuRobin A Felder

Published in: Breast cancer : basic and clinical research (2021)

GRK4 acts as an independent proliferation promotor in breast cancer. Our results suggest that targeted inhibition of GRK4 could be a new therapy for both hypertension and breast cancer.

Keyphrases

blood pressure
signaling pathway
genome wide
gene expression
copy number
dna methylation
genome wide analysis