Prescription opioid treatment for non-cancer pain and initiation of injection drug use: large retrospective cohort study.
James WiltonYounathan AbdiaMei ChongMohammad Ehsanul KarimStanley WongAaron MacInnesRob BalshawBin ZhaoTara GomesAmanda YuMaria AlvarezRichard C DartMel KrajdenJane A BuxtonNaveed Z JanjuaRoy PurssellPublished in: BMJ (Clinical research ed.) (2021)
The rate of IDU initiation among individuals who received chronic prescription opioid treatment for non-cancer pain was infrequent overall (3-4% within five years) but about eight times higher than among opioid naive individuals. These findings could have implications for strategies to prevent IDU initiation, but should not be used as a reason to support involuntary tapering or discontinuation of long term prescription opioid treatment.