Aromatase Inhibitors as Adjuvant Treatment for ER/PgR Positive Stage I Endometrial Carcinoma: A Retrospective Cohort Study.

Laura PaleariMariangela RutiglianiGiacomo Siri Nicoletta ProvincialiNicoletta ColomboAndrea Decensi

Published in: International journal of molecular sciences (2020)

Compared with no treatment, AI exhibited a trend toward a benefit on PFS and OS in patients with early stage hormone receptor-positive EC. Given the exploratory nature of our study, randomized clinical trials for ER/PgR positive EC patients are warranted to assess the clinical benefit of AI and the potential predictive role of steroid receptors and Ki-67.

Keyphrases

early stage
end stage renal disease
newly diagnosed
chronic kidney disease
clinical trial
squamous cell carcinoma
climate change
prognostic factors
patient reported outcomes
neoadjuvant chemotherapy
breast cancer cells
endoplasmic reticulum
sentinel lymph node
replacement therapy
locally advanced