Polymer-Based Graphene Derivatives and Microwave-Assisted Silver Nanoparticles Decoration as a Potential Antibacterial Agent.
Angelo NicosiaFabiana VentoAnna Lucia PellegrinoVáclav RancAnna PipernoAntonino MazzagliaPlacido Giuseppe MineoPublished in: Nanomaterials (Basel, Switzerland) (2020)
Nanocomposites obtained by the decoration of graphene-based materials with silver nanoparticles (AgNPs) have received increasing attention owing to their antimicrobial activity. However, the complex synthetic methods for their preparation have limited practical applications. This study aims to synthesize novel NanoHybrid Systems based on graphene, polymer, and AgNPs (namely, NanoHy-GPS) through an easy microwave irradiation approach free of reductants and surfactants. The polymer plays a crucial role, as it assures the coating layer/substrate compatibility making the platform easily adaptable for a specific substrate. AgNPs' loading (from 5% to 87%) can be tuned by the amount of Silver salt used during the microwave-assisted reaction, obtaining spherical AgNPs with average sizes of 5-12 nm homogeneously distributed on a polymer-graphene nanosystem. Interestingly, microwave irradiation partially restored the graphene sp2 network without damage of ester bonds. The structure, morphology, and chemical composition of NanoHy-GPS and its subunits were characterized by means of UV-vis spectroscopy, thermal analysis, differential light scattering (DLS), Field Emission Scanning Electron Microscopy (FE-SEM), Energy Dispersive X-ray analysis (EDX), Atomic Force Microscopy (AFM), and High-Resolution Transmission Electron Microscopy (HRTEM) techniques. A preliminary qualitative empirical assay against the typical bacterial load on common hand-contacted surfaces has been performed to assess the antibacterial properties of NanoHy-GPS, evidencing a significative reduction of bacterial colonies spreading.
Keyphrases
- silver nanoparticles
- electron microscopy
- high resolution
- atomic force microscopy
- carbon nanotubes
- room temperature
- high speed
- walled carbon nanotubes
- systematic review
- single molecule
- reduced graphene oxide
- high throughput
- computed tomography
- mass spectrometry
- gold nanoparticles
- magnetic resonance
- photodynamic therapy
- staphylococcus aureus
- climate change
- radiofrequency ablation
- tandem mass spectrometry
- escherichia coli
- gas chromatography
- single cell
- aqueous solution
- solid phase extraction
- network analysis
- liquid chromatography
- neural network
- molecularly imprinted