Oxidative couplings on tryptophan-based diketopiperazines leading to fused and bridged chemotypes.

Lorena Mendive-TapiaArantxa Albornoz-GradosAlexandra Bertran Fernando Albericio Rodolfo Lavilla

Published in: Chemical communications (Cambridge, England) (2018)

New chemotypes are obtained from tryptophan-containing diketopiperazines through selective C-C or C-N intramolecular oxidative couplings. The choice of the oxidant source dictates the outcome of the reaction.

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