Cold exposure increases circulating fibroblast growth factor 21 in the evening in males and females.
Carlijn A HoekxBorja Martinez-TellezMaaike E StraatMagdalena M A VerkleijMirjam KemmerenSander KooijmanMartin UhrbomSaskia C A de JagerPatrick C N RensenMariëtte R BoonPublished in: Endocrine connections (2024)
Cold exposure increased serum FGF21 levels in the evening, but not in the morning, in both males and females. GDF15 levels were not affected by cold exposure. Thus, this study suggests that the timing of cold exposure may influence cold-induced changes in FGF21 levels but not GDF15 levels and seems to be independent of changes in energy expenditure.
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