DNA methylation of CpG sites in the chicken KLF7 promoter and Exon 2 in association with mRNA expression in abdominal adipose tissue and blood metabolic indicators.

Zhiwei ZhangCunxi NieYuechan ChenYanzhe DongTao Lin

Published in: BMC genetics (2020)

In conclusion, the KLF7 transcripts of chicken abdominal adipose tissue might be inhibited by DNA methylation in the promoter, and it might be related to the DNA methylation level of PCpG6.

Keyphrases

dna methylation
adipose tissue
genome wide
gene expression
insulin resistance
transcription factor
high fat diet
copy number
type diabetes
skeletal muscle