Validating a novel three-times-weekly post-hemodialysis ceftriaxone regimen in infected Indigenous Australian patients-a population pharmacokinetic study.
Danny TsaiBetty B ZamCarleigh TongsFabian ChiongCherian SajivBasant PawarAadith AshokBrynley P CooperSteven Y C TongSonja JansonSteven C WallisJason Alexander RobertsSuzanne L ParkerPublished in: The Journal of antimicrobial chemotherapy (2023)
A novel 2 g three-times-weekly post-dialysis ceftriaxone regimen can be recommended for a bacterial infection with an MIC ≤1 mg/L. A 1 g three-times-weekly post-dialysis regimen is recommended for those with serum bilirubin ≥10 µmol/L. Administration of ceftriaxone during dialysis is not recommended.