SCONCE2: jointly inferring single cell copy number profiles and tumor evolutionary distances.

Published in: BMC bioinformatics (2022)

SCONCE2 jointly estimates copy number profiles and a distance metric for inferring tumor phylogenies in single cell whole genome tumor sequencing across multiple cells, enabling deeper understandings of tumor evolution.

Keyphrases

copy number
single cell
mitochondrial dna
genome wide
rna seq
high throughput