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Myositis autoantibodies in Iranian myositis patients: assessment the frequency and clinical relevancy.

Milad EbrahimiAbdolrahman RostamianRamin Rafiei-LatianeeSeyed Reza NajafizadehShafieh MovaseghiSeyedeh Tahereh FaeziTooba Ghazanfari
Published in: Clinical rheumatology (2021)
Taken together, it can be concluded that certain myositis autoantibodies present clinical significance which is in line with the literature. The use of these autoantibodies as biomarkers by line blotting along with indirect immunofluorescence facilitates diagnosis of inflammatory myopathies and makes it more accurate as well as better management of myositis patients if used based on a science-based manner. Key Points • Identification of MSAs and MAAs facilitates the diagnosis of inflammatory myopathies and provides better myositis patient's management if used according to a science-based manner. • Anti-rod and ring antibody was detected in a patient with ovarian cancer-induced dermatomyositis. • Malignancy and ILD are integrated parts of myositis which can be associated with MSAs and MAAs.
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