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Eleven-marker 10-color flow cytometric assessment of measurable residual disease for T-cell acute lymphoblastic leukemia using an approach of exclusion.

Prashant Ramesh TembhareGaurav ChatterjeeTwinkle KhankaSitaram GhogaleYajamanam BadrinathNilesh DeshpandeDevasis PandaNikhil V PatkarGaurav NarulaKarishma GiraseShefali VermaMahima SanyalHarshini N SriramShripad BanavaliSumeet GujralPapagudi G Subramanian
Published in: Cytometry. Part B, Clinical cytometry (2020)
We described an 11-marker 10-color MFC-based highly sensitive MRD assay in T-ALL using an approach of exclusion. The addition of CD4 and CD8 to the pan-T-cell markers in a 10-color assay is highly useful in T-ALL MRD assessment and extends its applicability to almost all T-ALL patients.
Keyphrases
  • acute lymphoblastic leukemia
  • end stage renal disease
  • high throughput
  • ejection fraction
  • newly diagnosed
  • chronic kidney disease
  • prognostic factors
  • high resolution
  • single cell
  • solid phase extraction