TLR4 Receptor D299G/T399I Haplotype Polymorphism Is Associated with Insulin Resistance in Obese Female Subjects.

Elham SharifMariam AlwakeelAfnan MohamedAbdelhamid KerkadiNasser Moustafa Rizk

Published in: Genes (2020)

TLR4 D299G/T399I haplotype polymorphism is associated with an increased risk of insulin resistance with the upregulation of TLR4 protein expression in obese subjects.

Keyphrases

toll like receptor
inflammatory response
adipose tissue
insulin resistance
metabolic syndrome
immune response
type diabetes
weight loss
nuclear factor
high fat diet
cell proliferation
signaling pathway
high fat diet induced