Impact of Frailty and Prefrailty on Outcomes of Transcatheter or Surgical Aortic Valve Replacement.
Suzanne V ArnoldYanglu ZhaoMartin B LeonJanar SathananthanMaria AluVinod H ThouraniCraig R SmithMichael J MackDavid J CohenPublished in: Circulation. Cardiovascular interventions (2022)
In a cohort of older patients with severe aortic stenosis who were at low or intermediate surgical risk, increasing frailty markers were associated with worse 2-year mortality and greater health status impairment after either TAVR or SAVR, but there were no significant interactions between type of valve replacement and frailty with respect to either outcome.
Keyphrases
- aortic stenosis
- aortic valve replacement
- community dwelling
- transcatheter aortic valve replacement
- aortic valve
- ejection fraction
- transcatheter aortic valve implantation
- left ventricular
- coronary artery disease
- cardiovascular events
- heart failure
- early onset
- risk factors
- mitral valve
- skeletal muscle
- cardiovascular disease
- atrial fibrillation
- insulin resistance
- metabolic syndrome
- glycemic control
- type diabetes