Cooperatively inhibition effect of miR-143-5p and miR-145-5p in tumorigenesis of glioblastoma cells through modulating AKT signaling pathway.

Sheyda Jodeiry ZaerMahmoudreza AghamaaliMohammad AminiMohammad Amin DoustvandiSeyed Samad HosseiniBehzad BaradaranSouzan NajafiYalda Baghay EsfandyariAmir Ali Mokhtarzadeh

Published in: BioImpacts : BI (2023)

In conclusion, miR-143 and miR-145 were indicated to show cooperative anti- cancer effects on glioblastoma cells via modulating AKT signaling as a new therapeutic approach.

Keyphrases

signaling pathway
induced apoptosis
cell proliferation

pi k akt
cell cycle arrest
long non coding rna

epithelial mesenchymal transition
long noncoding rna

endoplasmic reticulum stress
cell death