Plasma from patients with pulmonary embolism show aggregates that reduce after anticoagulation.

Stephen R BakerGeorgia HallidayMichal ZąbczykGhadir AlkarithiFraser L MacraeAnetta UndasBeverley J HuntRobert A S Ariëns

Published in: Communications medicine (2023)

These data corroborate the existence of microclots or aggregates in diseases associated with venous thromboembolism. Important questions are raised regarding their pathophysiological relevance and further studies are warranted to investigate whether they represent cause or consequence of clinical thrombosis.

Keyphrases

pulmonary embolism
venous thromboembolism
inferior vena cava
direct oral anticoagulants
electronic health record
atrial fibrillation
big data
case control
machine learning
data analysis